NEW APPROACHES TO COMBAT PORPHYROMONAS GINGIVALIS BIOFILMS

New approaches to combat Porphyromonas gingivalis biofilms

In nature, bacteria predominantly reside in structured, surface-attached communities embedded in a self-produced, extracellular matrix.These so-called biofilms play an important role in the development and pathogenesis of many infections, as they are difficult shampoo bar to eradicate due to their resistance to antimicrobials and host defense mecha

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IGLOO: An Iterative Global Exploration and Local Optimization Algorithm to Find Diverse Low-Energy Conformations of Flexible Molecules

The exploration shampoo bar of the energy landscape of a chemical system is essential for understanding and predicting its observable properties.In most cases, this is a challenging task due to the high complexity of such landscapes, which often consist of multiple, possibly hierarchical basins that are difficult to locate and thoroughly explore.In

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